RNA Details
Disease Name
diabetic cardiomyopathy
Tissue
heart
RNA Symbol
miR-471-3p
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
RT-PCR;western blotting;dual luciferase reporter assay etc.
Target
SIRT1
Pathway
NA
PubMed ID
Title
The effect of miR-471-3p on macrophage polarization in the development of diabetic cardiomyopathy
Year
2021
Function
The development of diabetic cardiomyopathy was related to advanced glycation end products-induced macrophage polarized to M1 type through a mechanism involving the miR-471-3p/SIRT1 pathway.